| TFEB controls syncytiotrophoblast formation and hormone production in placenta Cesana M, Tufano G, Panariello F, Zampelli N, Soldati C, Mutarelli M, Montefusco S, Grieco G, Sepe LV, Rossi B, Nusco E, Rossignoli G, Panebianco G, Merciai F, Salviati E, Sommella EM, Campiglia P, Martello G, Cacchiarelli D, Medina DL, Ballabio A. Cell Death and Differentiation 2024 doi |
| Unraveling the impact of ZZZ3 on the mTOR/ribosome pathway in human embryonic stem cells homeostasis Lo Conte M, Lucchino V, Scalise S, Zannino C, Valente D, Rossignoli G, Murfuni MS, Cicconetti C, Scaramuzzino L, Matassa DS, Procopio A, Martello G, Cuda G, Parrotta EI. Stem Cell Reports 2024 19:729-743 doi |
| The rules of the totipotency treasure hunt Martello, G. Nature Cell Biology 2024 doi |
| Identification of druggable host dependency factors shared by multiple SARS-CoV-2 variants of concern Frasson I, Diamante L, Zangrossi M, Carbognin E, Dalla Pietà A, Penna A, Rosato A, Verin R, Torrigiani F, Salata C, Dizanzo MP, Vaccaro L, Cacchiarelli D, Richter SN, Montagner M, Martello G. Journal of Molecular Cell Biology 2024 doi |
| TGF-beta dynamically controls epithelial identity in a 3D model of human epiblast Zorzan I, Carbognin E, Lauria A, Proserpio V, Benvegnù D., Dalrio C, Arboit M, Paolucci I, Drusin A, Sledziowska M, Amadei G, Oliviero S, Martello G. bioRxiv 2023 12.07.570575 doi |
| KLF7 is a general inducer of human pluripotency Arboit M, Zorzan I, Pellegrini M, Martini P, Carbognin E, Martello G. bioRxiv 2023 09.06.556189 doi |
| STAT3-dependent long non-coding RNA Lncenc1 contributes to mouse ES cells pluripotency via stabilizing K mRNA Monteleone E, Corrieri P, Provero P, Viavattene D, Pulvirenti L, Raggi L, Carbognin E, Bianchi ME, Martello G, Oliviero S, Pandolfi PP, Poli V. Briefings in Functional Genomics 2023. doi |
| STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia Dinarello A, Betto RM, Diamante L, Tesoriere A, Ghirardo R, Cioccarelli L, Meneghetti G, Peron M, Laquatra C, Tiso N, Martello G, Argenton F. Cell Death Discovery 2023, 9: 226. doi |
| Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity Ferlazzo GM, Gambetta AM, Amato S, Cannizzaro N, Angiolillo S, Arboit M, Diamante L, Carbognin E, Romani P, La Torre F, Galimberti E, Pflug F, Luoni M, Giannelli S, Pepe G, Capocci L, Di Pardo A, Vanzani P, Zennaro L, Broccoli V, Leeb M, Moro E, Maglione V, Martello G. Nat Commun 2023, 14: 3962. doi |
| New permanent stem cell niche for development and regeneration in a chordate Vanni V, Caicci F, Peronato A, Martello G, Asnicar D, Gasparini F, Ballarin L, Manni L. bioRxiv 2023 05.15.540819. doi |
| Esrrb guides naive pluripotent cells through the formative transcriptional programme Carbognin E, Carlini V, Panariello F, Chieregato M, Guerzoni E, Benvegnù D, Perrera V, Malucelli C, Cesana M, Grimaldi A, Mutarelli M, Carissimo A, Tannenbaum E, Kugler H, Hackett JA, Cacchiarelli D, Martello G. Nature Cell Biology 2023. doi |
| Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation Zorzan I, Betto RM, Rossignoli G, Arboit M, Drusin A, Corridori C, Martini P, Martello G. EMBO reports 2023 e55235. doi |
| Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro Kraunsoe S, Azami T, Pei Y, Martello G, Jones K, Boroviak T, Nichols J. Biology Open 2023 Jan;12(1):bio059650. doi (Epub 2023 Jan 17) |
| 3D ECM-rich environment sustains the identity of naive human iPSCs Cesare E, Urciuolo A, Stuart HT, Torchio E, Gesualdo A, Laterza C, Gagliano O, Martewicz S, Cui M, Manfredi A, Di Filippo L, Sabatelli P, Squarzoni S, Zorzan I, Betto RM, Martello G, Cacchiarelli D, Luni C, Elvassore N. Cell Stem Cell 2022 Dec;29(12):1703-1717.e7. doi |
| Metabolic regulation in pluripotent stem cells Diamante L, Martello G. Current Opinion in Genetics & Development 2022 Aug;75:101923. doi |
| Distinct phospho-variants of STAT3 regulate naïve pluripotency and developmental pace in vivo Azami T, Kraunsoe S, Martello G, Pei Y, Boroviak T, Nichols J. bioRxiv 2022.03.08.483469 doi |
| Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance Romani P, Nirchio N, Arboit M, Barbieri V, Tosi A, Michielin F, Shibuya S, Benoist T, Wu D, Hindmarch CCT, Giomo M, Urciuolo A, Giamogante F, Roveri A, Chakravarty P, Montagner M, Calì T, Elvassore N, Archer SL, De Coppi P, Rosato A, Martello G, Dupont S. Nature Cell Biology 2022 Feb;24(2):168-180. doi (Epub 2022 Feb 14) |
| Using Microfluidics to Generate Human Naïve and Primed Pluripotent Stem Cells Zorzan I, Gagliano O, Elvassore N, Martello G. Methods in Molecular Biology 2022;2416:53-71. doi |
| BrewerIX enables allelic expression analysis of imprintedand X-linked genes from bulk and single-cell transcriptomes Martini P., Sales G., Diamante L., Perrera V., Colantuono C., Riccardo S., Cacchiarelli D., Romualdi C., Martello G. Communications Biology volume 5, Article number: 146 (2022). doi |
| STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia Dinarello A., Betto R.M., Cioccarelli C., Diamante L., Meneghetti G., Peron M., Tesoriere A., Laquatra C., Tiso N., Martello G., Argenton F. bioRxiv 2021.11.19.469257. doi |
| PsiNorm: a scalable normalization for single-cell RNA-seq data Matteo Borella, Graziano Martello, Davide Risso, Chiara Romualdi Bioinformatics 2021 Sep 9:btab641. doi |
| Y705 and S727 are required for the mitochondrial import and transcriptional activities of STAT3, and for regulation of stem cell proliferation Margherita Peron, Alberto Dinarello, Giacomo Meneghetti, Laura Martorano, Riccardo M Betto, Nicola Facchinello, Annachiara Tesoriere, Natascia Tiso, Graziano Martello, Francesco Argenton Development 2021 Sep 1;148(17):dev199477. doi |
| Metabolic control of DNA methylation in naive pluripotent cells Riccardo M. Betto, Linda Diamante, Valentina Perrera, Matteo Audano, Stefania Rapelli, Andrea Lauria, Danny Incarnato, Mattia Arboit, Silvia Pedretti, Giovanni Rigoni, Vincent Guerineau, David Touboul, Giuliano Giuseppe Stirparo, Tim Lohoff, Thorsten Boroviak, Paolo Grumati, Maria E. Soriano, Jennifer Nichols, Nico Mitro, Salvatore Oliviero & Graziano Martello Nature Genetics 2021. doi |
| Mitochondrial STAT3 regulates proliferation of tissue stem cells Peron M, Meneghetti G, Dinarello A, Martorano L, Betto RM, Facchinello N, Tiso N, Martello G, Argenton F bioRxiv 2020.07.17.208264. doi |
| Embryonic stem cells commit to differentiation by symmetric divisions following a variable lag period Strawbridge SE, Blanchard GB, Smith A, Kugler H, Martello G bioRxiv 2020.06.17.157578. doi |
| Allelic expression analysis of Imprinted and X-linked genes from bulk and single-cell transcriptomes Martini P, Sales G, Perrera V, Diamante L, Romualdi C, Martello G bioRxiv 2020.05.20.105841. doi |
| Esrrb Conveys Naïve Pluripotent Cells Through The Formative Transcriptional Program Carbognin E, Carlini V, Panariello F, Perrera V, Malucelli C, Cesana M, Mutarelli M, Carissimo A, Hackett JA, Cacchiarelli D, Martello G. Available at SSRN |
| The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs Zorzan I, Pellegrini M, Arboit M, Incarnato D, Maldotti M, Forcato M, Tagliazucchi GM, Carbognin E, Montagner M, Oliviero S, Martello G. Nature Communications 2020 May 12;11(1):2364. doi |
| How Does Reprogramming to Pluripotency Affect Genomic Imprinting? Perrera V, Martello G. Frontiers in Cell and Developmental Biology 2019 May 9;7:76. doi |
| Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics Giulitti S, Pellegrini M, Zorzan I, Martini P, Gagliano O, Mutarelli M, Ziller MJ, Cacchiarelli D, Romualdi C, Elvassore N, Martello G. Nature Cell Biology 2019 Feb;21(2):275-286. doi |
| A common molecular logic determines embryonic stem cell self-renewal and reprogramming Dunn SJ, Li MA, Carbognin E, Smith A, Martello G. EMBO Journal 2019 Jan 3;38(1):e100003. doi |
| A Method to Identify and Analyze Biological Programs through Automated Reasoning Yordanov B, Dunn SJ, Kugler H, Smith A, Martello G, Emmott S. Nature Systems Biology and Applications 2016 Jul 7;2:16010. doi |
| Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency Carbognin E, Betto RM, Soriano ME, Smith AG, Martello G. EMBO Journal 2016 Mar 15;35(6):618-34. doi |
| The nature of embryonic stem cells Martello G, Smith A. Annual Review of Cell and Developmental Biology 2014;30:647-75. doi |
| Defining an essential transcription factor program for naïve pluripotency Dunn SJ, Martello G, Yordanov B, Emmott S, Smith AG. Science 2014 Jun 6;344(6188):1156-1160. doi |
| Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor Martello G, Bertone P, Smith A. EMBO Journal 2013 Oct 2;32(19):2561-74. doi |
| Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal Martello G, Sugimoto T, Diamanti E, Joshi A, Hannah R, Ohtsuka S, Göttgens B, Niwa H, Smith A. Cell Stem Cell 2012 Oct 5;11(4):491-504. doi |
Publications since 2016 are supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 716910).