Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance Romani P, Nirchio N, Arboit M, Barbieri V, Tosi A, Michielin F, Shibuya S, Benoist T, Wu D, Hindmarch CCT, Giomo M, Urciuolo A, Giamogante F, Roveri A, Chakravarty P, Montagner M, Calì T, Elvassore N, Archer SL, De Coppi P, Rosato A, Martello G, Dupont S. Nat Cell Biol. 2022 Feb;24(2):168-180. doi (Epub 2022 Feb 14) |
Using Microfluidics to Generate Human Naïve and Primed Pluripotent Stem Cells Zorzan I, Gagliano O, Elvassore N, Martello G. Methods Mol Biol. 2022;2416:53-71. doi |
BrewerIX enables allelic expression analysis of imprintedand X-linked genes from bulk and single-cell transcriptomes Martini P., Sales G., Diamante L., Perrera V., Colantuono C., Riccardo S., Cacchiarelli D., Romualdi C., Martello G. Communications Biology volume 5, Article number: 146 (2022). doi |
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia Dinarello A., Betto R.M., Cioccarelli C., Diamante L., Meneghetti G., Peron M., Tesoriere A., Laquatra C., Tiso N., Martello G., Argenton F. bioRxiv 2021.11.19.469257. doi |
PsiNorm: a scalable normalization for single-cell RNA-seq data Matteo Borella, Graziano Martello, Davide Risso, Chiara Romualdi Bioinformatics 2021 Sep 9:btab641. doi |
Y705 and S727 are required for the mitochondrial import and transcriptional activities of STAT3, and for regulation of stem cell proliferation Margherita Peron, Alberto Dinarello, Giacomo Meneghetti, Laura Martorano, Riccardo M Betto, Nicola Facchinello, Annachiara Tesoriere, Natascia Tiso, Graziano Martello, Francesco Argenton Development 2021 Sep 1;148(17):dev199477. doi |
Metabolic control of DNA methylation in naive pluripotent cells Riccardo M. Betto, Linda Diamante, Valentina Perrera, Matteo Audano, Stefania Rapelli, Andrea Lauria, Danny Incarnato, Mattia Arboit, Silvia Pedretti, Giovanni Rigoni, Vincent Guerineau, David Touboul, Giuliano Giuseppe Stirparo, Tim Lohoff, Thorsten Boroviak, Paolo Grumati, Maria E. Soriano, Jennifer Nichols, Nico Mitro, Salvatore Oliviero & Graziano Martello Nature Genetics 2021. doi |
Mitochondrial STAT3 regulates proliferation of tissue stem cells Peron M, Meneghetti G, Dinarello A, Martorano L, Betto RM, Facchinello N, Tiso N, Martello G, Argenton F bioRxiv 2020.07.17.208264. doi |
Embryonic stem cells commit to differentiation by symmetric divisions following a variable lag period Strawbridge SE, Blanchard GB, Smith A, Kugler H, Martello G bioRxiv 2020.06.17.157578. doi |
Allelic expression analysis of Imprinted and X-linked genes from bulk and single-cell transcriptomes Martini P, Sales G, Perrera V, Diamante L, Romualdi C, Martello G bioRxiv 2020.05.20.105841. doi |
Esrrb Conveys Naïve Pluripotent Cells Through The Formative Transcriptional Program Carbognin E, Carlini V, Panariello F, Perrera V, Malucelli C, Cesana M, Mutarelli M, Carissimo A, Hackett JA, Cacchiarelli D, Martello G. Available at SSRN |
The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs Zorzan I, Pellegrini M, Arboit M, Incarnato D, Maldotti M, Forcato M, Tagliazucchi GM, Carbognin E, Montagner M, Oliviero S, Martello G. Nature Communications 2020 May 12;11(1):2364. doi |
How Does Reprogramming to Pluripotency Affect Genomic Imprinting? Perrera V, Martello G. Frontiers in Cell and Developmental Biology 2019 May 9;7:76. doi |
Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics Giulitti S, Pellegrini M, Zorzan I, Martini P, Gagliano O, Mutarelli M, Ziller MJ, Cacchiarelli D, Romualdi C, Elvassore N, Martello G. Nature Cell Biology 2019 Feb;21(2):275-286. doi |
A common molecular logic determines embryonic stem cell self-renewal and reprogramming Dunn SJ, Li MA, Carbognin E, Smith A, Martello G. EMBO Journal 2019 Jan 3;38(1):e100003. doi |
A Method to Identify and Analyze Biological Programs through Automated Reasoning Yordanov B, Dunn SJ, Kugler H, Smith A, Martello G, Emmott S. Nature Systems Biology and Applications 2016 Jul 7;2:16010. doi |
Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency Carbognin E, Betto RM, Soriano ME, Smith AG, Martello G. EMBO Journal 2016 Mar 15;35(6):618-34. doi |
The nature of embryonic stem cells Martello G, Smith A. Annual Review of Cell and Developmental Biology 2014;30:647-75. doi |
Defining an essential transcription factor program for naïve pluripotency Dunn SJ, Martello G, Yordanov B, Emmott S, Smith AG. Science 2014 Jun 6;344(6188):1156-1160. doi |
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor Martello G, Bertone P, Smith A. EMBO Journal 2013 Oct 2;32(19):2561-74. doi |
Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal Martello G, Sugimoto T, Diamanti E, Joshi A, Hannah R, Ohtsuka S, Göttgens B, Niwa H, Smith A. Cell Stem Cell 2012 Oct 5;11(4):491-504. doi |
Publications since 2016 are supported by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 716910).